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Maternal Serum Screening

Second Trimester Maternal Serum Screening
Serum Integrated Screen

These biochemical screening tests incorporate clinical information to calculate a pregnancy-specific risk for open neural tube defect and trisomy 21 (Down syndrome). An estimated 85% of open neural tube defects and about 75%-80% of trisomy 21 can be detected by these tests. The American College of Obstetrics and Gynecologists recommends that all pregnant women be offered this test.